1. Scripps Research Institute Scientists Identify First Potentially Effective Therapy for Human Prion Disease   
  2. Probe from SRIMSC Enters Phase II/III Clinical trials.   
  3. The Scripps Molecular Screening Center becomes the first to have 1000 AIDs in PubChem!   
  4. Receptos Scientists Publish Determination of a High Resolution S1P1 Structure in Science   
  5. NIH Common Fund researchers uncover structure of important target for drug design   
  6. NIH Research Matters: Designing New Diabetes Drugs   
  7. Discovery of a treatable mechanism for avoiding the deadly response to flu: North County Times, Eurekalert [1, 2]    
  8. Nature: Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand   
  9. Scripps Research and MIT scientists discover class of potent anti-cancer compounds    
  10. MLP Probe Project Leads to First in Human Studies    
  11. Business Wire:   Receptos Initiates Clinical Trials for S1P1 Agonist Program, Aimed at Multiple Sclerosis   
  12. Nature:   Quantitative reactivity profiling predicts functional cysteines in proteomes.

  13. Nature:   Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARc by Cdk5.
  14. Discovery and optimization of chemical probes to define important molecular signals in medicine.
  15. Nature Reviews Drug Discovery article:   Chemical modulators of S1P receptors as barrier-oriented therapeutic molecules.
  16. Nature Chemical Biology article: S1P1 signaling just keeps going and going and going…
  17. Nature Biotechnology article:   Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes.
Home » Probes » Probe Reports
Probes

Below is a table of publicly available probes generated by the Scripps Center. Click on a row in the table for a summary, including primary publication, PubChem Summary AID, Probe Report and NCBI Bookshelf link (where available).

Please note the number of publicly available probe reports is less than the actual amount that we have authored. This is due to a variety of reasons, including requests from our collaborators to embargo probe report publication, as well as the process of submitting probe reports for publication in PubMed.

There are currently 42 probe reports (63 probes identified) that are referenced below:

 


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