1. Discovery and optimization of chemical probes to define important molecular signals in medicine.
  2. Nature Reviews Drug Discovery article:   Chemical modulators of S1P receptors as barrier-oriented therapeutic molecules.   
  3. Nature Chemical Biology article: S1P1 signaling just keeps going and going and going…   
  4. Nature Biotechnology article:   Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes.   
Home » Publications » Outreach Publications
Outreach Publications
Cahalan S., and Rosen H.
S1P1 signaling just keeps going and going and going…
 
Fazilleau N., McHeyzer-Williams L., Rosen H., and McHeyzer-Wilaims M.
Follicular helper T cell function is regulated by the strength of TCR binding.

8 Google Scholar Citations
 
Marsolais, D., and Rosen H.
Chemical modulators of S1P receptors as barrier-oriented therapeutic molecules
 
Rosen, H., Gozalez-Cabrera P., Sanna M., and Brown S.
Sphingosine 1-phosphate receptor signaling.

4 Google Scholar Citations
 
Marsolais D, Hahm B, Walsh KB, Edelmann KH, McGavern D, Hatta Y, Kawaoka Y, Rosen H, Oldstone MB.
A critical role for the sphingosine analog AAL-R in dampening the cytokine response during influenza virus infection.

3 Google Scholar Citations
 
Don AS, Rosen H.
A lipid binding domain in sphingosine kinase 2.
 
Niessen F, Furlan-Freguia C, Fernandez JA, Mosnier LO, Castellino FJ, Weiler H, Rosen H, Griffin JH, Ruf W.
Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality.

9 Google Scholar Citations
 


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