Karapetyan et al.
A novel drug screening approach for prion diseases identifies tacrolimus and astemizole as anti-prion agents.
5 Google Scholar Citations
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Khan SH, Awasthi S, Guo C, Goswami D, Ling J, Griffin PR, Simons SS Jr, Kumar R.
Binding of the N-terminal region of coactivator TIF2 to the intrinsically disordered AF1 domain of the glucocorticoid receptor is accompanied by conformational reorganizations.
5 Google Scholar Citations
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Cahalan SM, Gonzalez-Cabrera PJ, Nguyen N, Guerrero M, George Cisar EA, Leaf NB, Brown SJ, Roberts E, Rosen H.
S1P1 Receptor Upregulation and Amelioration of Experimental Autoimmune Encephalomyelitis by an S1P1 Antagonist.
 0 Google Scholar Citations |
Pascal BD, Willis S, Lauer JL, Landgraf RR, West GM, Marciano D, Novick S, Goswami D, Chalmers MJ, Griffin PR.
HDX workbench: software for the analysis of H/D exchange MS data.
1 Google Scholar Citation |
Adibekian A, Martin BR, Chang JW, Hsu KL, Tsuboi K, Bachovchin DA, Speers AE, Brown SJ, Spicer T, Fernandez-Vega V, Ferguson J, Hodder PS, Rosen H, Cravatt BF.
Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes.
4 Google Scholar Citations |
Sarkisyan G, Cahalan S, Gonzalez-Cabrera P, Leaf N, Rosen H.
Real-time differential labeling of blood, interstitium and lymphatic and single-field analysis of vasculature dynamics in vivo.
0 Google Scholar Citations |
Gonzalez-Cabrera PJ, Cahalan SM, Nguyen N, Sarkisyan G, Leaf NB, Cameron MD, Kago T, Rosen H.
S1P(1) receptor modulation with cyclical recovery from lymphopenia ameliorates mouse model of multiple sclerosis.
3 Google Scholar Citations |
Rillahan CD, Brown SJ, Register AC, Rosen H, Paulson JC.
High-throughput screening for inhibitors of sialyl- and fucosyltransferases.
5 Google Scholar Citations |
Guerrero M, Urbano M, Zhao J, Crisp M, Chase P, Hodder P, Schaeffer MT, Brown S, Rosen H, Roberts E.
Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P?-R) agonists.
1 Google Scholar Citation |
Peatey CL, Spicer T, Hodder P, Trenholme KR, Gardiner DL.
A high-throughput assay for the identification of drugs against late-stage Plasmodium falciparum gametocytes.
9 Google Scholar Citations |
Iwasaki A, Medzhitov R.
A new shield for a cytokine storm.
3 Google Scholar Citations |
Teijaro JR, Walsh KB, Cahalan S, Fremgen DM, Roberts E, Scott F, Martinborough E, Peach R, Oldstone MB, Rosen H.
Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection.
49 Google Scholar Citations |
Urbano M, Guerrero M, Zhao J, Velaparthi S, Schaeffer MT, Brown S, Rosen H, Roberts E.
SAR analysis of innovative selective small molecule antagonists of sphingosine-1-phosphate 4 (S1P?) receptor.
3 Google Scholar Citations |
Walsh KB, Teijaro JR, Wilker PR, Jatzek A, Fremgen DM, Das SC, Watanabe T, Hatta M, Shinya K, Suresh M, Kawaoka Y, Rosen H, Oldstone MB.
Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus.
20 Google Scholar Citations |
Baillargeon P, Scampavia L, Einsteder R, Hodder P
Monitoring of HTS Compound Library Quality via a High-Resolution Image Acquisition and Processing Instrument
0 Google Scholar Citations |
Chalmers MJ, Busby SA, Pascal BD, West GM, Griffin PR.
Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactions.
13 Google Scholar Citations |
Willis S, Griffin PR.
Mutual information identifies sequence positions conserved within the nuclear receptor superfamily: approach reveals functionally important regions for DNA binding specificity.
0 Google Scholar Citations |
Istrate MA, Spicer TP, Wang Y, Bernard JA, Helvering LM, Bocchinfuso WP, Richardson TI, Zink R, Kumar N, Montrose-Rafizadeh C, Dodge J, Hodder P, Griffin PR.
Development of an HTS-Compatible Assay for Discovery of ROR{alpha} Modulators Using AlphaScreen(R) Technology.
1 Google Scholar Citation |
Vidovic D., Busby S.A., Griffin P.R., Schürer S.C.
A Combined Ligand- and Structure-Based Virtual Screening Protocol Identifies Submicromolar PPAR? Partial Agonists
10 Google Scholar Citations |
Doghman M, Madoux F, Hodder P, Lalli E.
Identification and characterization of steroidogenic factor-1 inverse agonists.
1 Google Scholar Citation |
Weerapana E, Wang C, Simon GM, Richter F, Khare S, Dillon MB, Bachovchin DA, Mowen K, Baker D, Cravatt BF.
Quantitative reactivity profiling predicts functional cysteines in proteomes.
102 Google Scholar Citations |
Madoux F, Simanski S, Chase P, Mishra JK, Roush WR, Ayad NG, Hodder P.
An ultra-high throughput cell-based screen for wee1 degradation inhibitors.
4 Google Scholar Citations |
Chalmers MJ, Pascal BD, Willis S, Zhang J, Iturria SJ, Dodge JA, Griffin PR.
Methods for the Analysis of High Precision Differential Hydrogen Deuterium Exchange Data.
9 Google Scholar Citations |
Knuckley B, Jones JE, Bachovchin DA, Slack J, Causey CP, Brown SJ, Rosen H, Cravatt BF, Thompson PR.
A fluopol-ABPP HTS assay to identify PAD inhibitors.
14 Google Scholar Citations |
Noël R, Song X, Jiang R, Chalmers MJ, Griffin PR, Kamenecka TM.
Efficient methodology for the synthesis of 3-amino-1,2,4-triazoles.
5 Google Scholar Citations |
Dai SY, Burris TP, Dodge JA, Montrose-Rafizadeh C, Wang Y, Pascal BD, Chalmers MJ, Griffin PR.
Unique Ligand Binding Patterns Between Estrogen Receptor and Revealed by Hydrogen/Deuterium Exchange.
0 Google Scholar Citations |
Stephan C. Schürer, Steven J. Brown, Pedro Gonzales Cabrera, Marie-Therese Schaeffer, Jacqueline Chapman, Euijung Jo, Peter Chase, Tim Spicer, Peter Hodder and Hugh Rosen.
Ligand-binding pocket shape differences between S1P1 and S1P3 determine efficiency of chemical probe identification by uHTS.
2 Google Scholar Citations |
A.S. Don, H. Rosen.
A fluorescent plate reader assay for ceramide kinase.
0 Google Scholar Citations |
Lauer-Fields JL, Spicer TP, Chase PS, Cudic M, Burstein GD, Nagase H, Hodder P, Fields GB.
Screening of potential a disintegrin and metalloproteinase with thrombospondin motifs-4 inhibitors using a collagen model fluorescence resonance energy transfer substrate.
3 Google Scholar Citations |
Thomas Schröter, Dmitriy Minond, Amiee Weiser, Chinh Dao, Jeff Habel, Timothy Spicer, Peter Chase, Pierre Baillargeon, Louis Scampavia, Stephan Schürer, Caty Chung, Chris Mader, Mark Southern, Nick Tsinoremas, Philip LoGrasso and Peter Hodder.
Comparison of Miniaturized Time-Resolved Fluorescence Resonance Energy Transfer and Enzyme-Coupled Luciferase High-Throughput Screening Assays to Discover Inhibitors of Rho-Kinase II (ROCK-II).
5 Google Scholar Citations |
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