for NIH Molecular Libraries Program centers by assay submitter.
PubChem's data source information page can be found here.
Probe Reports (reported by Molecular Libraries website)
The Molecular Libraries Program website lists the publicly available Probe reports from all centers but has not been updated for a while. It can be found here. We keep our own up to date copy of Scripps' Center probes here.
Google Scholar Citations for PubMed
This tool will take a PubMed PMID and run a Google search to obtain the number of times it has been cited. The resulting Google Scholar link is inserted into the PubMed page as shown in the picture.
To use this tool you will need to be using the Firefox browser with the Greasemonkey extension installed. You can then install the tool here.
1,556 PubChem assays, 48,857,147 tested substances, 430,110 active substances, 72 probes and 141 publications, with 5435 citations
MS Drug Discovered at TSRI is Safe and Effective in Phase II Study
A compound discovered and synthesized in The Scripps Research Institute (TSRI) labs of Professors Hugh Rosen and Edward Roberts has provided positive results for safety and efficacy in Phase 2 clinical trials for relapsing multiple sclerosis, according to Receptos, the biopharmaceutical company developing the drug for approval by the US Food and Drug Administration.
“The Rosen and Roberts laboratories are very gratified to see these direct improvements in the lives of patients and families dealing with this debilitating illness,” said Rosen. “These data support our labs' approach at TSRI—that discovery of fundamental mechanisms in chemical biology provides the foundation for intelligent intervention in disease processes. Meeting the needs of patients and their families is our high calling in biomedical science.”
The drug candidate, RPC1063, was first discovered at TSRI from work in the National Institutes of Health (NIH) Molecular Libraries Initiative. The randomized, double-blind Phase 2 study assessed the efficacy, safety and tolerability of two orally administered doses of RPC1063 against placebo in 258 patients with relapsing multiple sclerosis across 77 sites in 13 countries. There was a highly statistically significant 86 percent reduction in MRI measures of disease activity.
A Phase 3 trial—a randomized, double-blind study involving 1,200 patients with relapsing multiple sclerosis—was launched in December 2013.